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Indapamide is an indole derivative of chlorosulphonamide and a sulfamyl diuretic with antihypertensive activity. Indapamide may interact directly with the subunits of delayed rectifier potassium channels, thereby blocking both slow and rapid K+ (IKs and IKr) currents through the channels.

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indapamide, Lozol: Drug Facts, Side Effects and Dosing

Indapamide is a thiazide-like in persons with high blood pressure and the thiazide-like and thiazide-type diuretics have similar rates of adverse effects.

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